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1.
Sci Rep ; 12(1): 20572, 2022 Nov 29.
Article in English | MEDLINE | ID: covidwho-2133641

ABSTRACT

The dynamics of human mobility have been known to play a critical role in the spread of infectious diseases like COVID-19. In this paper, we present a simple compact way to model the transmission of infectious disease through transportation networks using widely available aggregate mobility data in the form of a zone-level origin-destination (OD) travel flow matrix. A key feature of our model is that it not only captures the propagation of infection via direct connections between zones (first-order effects) as in most existing studies but also transmission effects that are due to subsequent interactions in the remainder of the system (higher-order effects). We demonstrate the importance of capturing higher-order effects in a simulation study. We then apply our model to study the first wave of COVID-19 infections in (i) Italy, and, (ii) the New York Tri-State area. We use daily data on mobility between Italian provinces (province-level OD data) and between Tri-State Area counties (county-level OD data), and daily reported caseloads at the same geographical levels. Our empirical results indicate substantial predictive power, particularly during the early stages of the outbreak. Our model forecasts at least 85% of the spatial variation in observed weekly COVID-19 cases. Most importantly, our model delivers crucial metrics to identify target areas for intervention.


Subject(s)
COVID-19 , Communicable Diseases , Humans , COVID-19/epidemiology , Transportation , Reproduction , Travel , Communicable Diseases/epidemiology
2.
Vaccine ; 40(15): 2242-2246, 2022 04 01.
Article in English | MEDLINE | ID: covidwho-1937278

ABSTRACT

India's mass vaccination efforts have been slow due to high levels of vaccine hesitancy. This study uses data from an online discrete choice experiment with 1371 respondents to rigorously examine the factors shaping vaccine preference in the country. We find that vaccine efficacy, presence of side effects, protection duration, distance to vaccination centre and vaccination rates within social network play a critical role in determining vaccine demand. We apply a non-parametric model to uncover heterogeneity in the effects of these factors. We derive two novel insights from this analysis. First, even though, on average, domestically developed vaccines are preferred, around 30% of the sample favours foreign-developed vaccines. Second, vaccine preference of around 15% of the sample is highly sensitive to the presence of side effects and vaccination uptake among their peer group. These results provide insights for the ongoing policy debate around vaccine adoption in India.


Subject(s)
COVID-19 Vaccines , COVID-19 , Humans , India , SARS-CoV-2 , Vaccination
3.
Transp Res Part A Policy Pract ; 160: 45-60, 2022 Jun.
Article in English | MEDLINE | ID: covidwho-1773815

ABSTRACT

The COVID-19 pandemic has drastically impacted people's travel behaviour and introduced uncertainty in the demand for public transport. To investigate user preferences for travel by London Underground during the pandemic, we conducted a stated choice experiment among its pre-pandemic users (N = 961). We analysed the collected data using multinomial and latent class logit models. Our discrete choice analysis provides two sets of results. First, we derive the crowding multiplier estimate of travel time valuation (i.e., the ratio of the value of travel time in uncrowded and crowded situations) for London underground users. The results indicate that travel time valuation of Underground users increases by 73% when it operates at technical capacity. Second, we estimate the sensitivity of the preference for the London Underground relative to the epidemic situation (confirmed new COVID-19 cases) and interventions (vaccination rates and mandatory face masks). The sensitivity analysis suggests that making face masks mandatory is a main driver for recovering the demand for the London underground. The latent class model reveals substantial preference heterogeneity. For instance, while the average effect of mandatory face masks is positive, the preferences of 30% of pre-pandemic users for travel by the Underground are negatively affected. The positive effect of mandatory face masks on the likelihood of taking the Underground is less pronounced among males with age below 40 years, and a monthly income below 10,000 GBP. The estimated preference sensitivities and crowding multipliers are relevant for supply-demand management in transit systems and the calibration of advanced epidemiological models.

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